A CME Journal for GPs and MD Physicians

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Mucocutaneous Drug Reactions

Panniculitis Painful, erythematous plaques had erupted 4 to 6 weeks earlier on the left upper arm and lower abdominal wall of a 54-year-old woman. The lesions had since increased in size and bec... More

Strong evidence supports the use of propranolol for migraine prevention

The pharmacologic treatment of migraine may be acute (abortive) or preventive (prophylactic), and patients with frequent severe headaches require both approaches. Effective migraine treatment begin... More

A pediatric rheumatologist who agreed with the diagnosis of idiopathic Raynaud phenomenon

Idiopathic Raynaud Disease In January, a 14-year-old girl presented with purple coloration of the distal toes. During the week and a half before presentation, she had redness and swelling just p... More

Caffeinated coffee is linked to reduced risk of colon cancer

There's a tremendous amount of research available on the benefits of drinking coffee. Much of that research has attributed its positive health effects on the large amounts of antioxidants it co... More

Cutaneous Manifestations of Diabetes Mellitus

Diabetes is the most common endocrine disorder, affecting 8.3% of the population (1). Skin disorders will be present in 79.2% of people with diabetes (2). A study of 750 patients with diabetes foun... More

Collecting Smaller Blood Samples for Testing May Benefit Patients but Pose Challenges for Labs

In 1999, Jocelyn M. Hicks, PhD, a laboratory director who was hospitalized for several months, developed anemia in the hospital and required several blood transfusions. After she recovered, she was... More

Study Suggests Blood Test May Predict Response to Antidepressants

British researchers have developed a blood test that may be able to predict whether patients dealing with depression will respond to common drugs used to treat the condition. If confirmed by larger... More

Fever and Productive Cough

What disorder could account for this clinical picture? Radiologic evidence of a response to antibiotic therapy was absent in a 48-year-old man with “pneumonitis.” He had a productive c... More

Nearly 50% of patients with type 2 Diabetes may develop heart failure

Almost 50% of patients with type 2 diabetes will develop heart failure. Data on the effects of glucose-lowering agents on heart failure outcomes have demonstrated that thiazolidinedione’s hav... More
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